ECOTOXICOLOGIE

De nombreuses banques de données disponibles sur STN sont en mesure de vous fournir des informations dans le domaine de l’écotoxicologie.

Ce domaine est particulièrement bien couvert :

- dans des banques de données bibliographiques telles que ESBIOBASE, TOXCENTER, PASCAL, CHEMICAL ABSTRACTS..

- dans les banques de données factuelles telles que BEILSTEIN et HSDB

Exemple : Retrouver des données écotoxicologiques sur le chlorphenamidine

1° Interrogation de la banque de données REGISTRY

La recherche va débuter dans le fichier REGISTRY qui est le répertoire des substances chimiques produit par CHEMICAL ABSTRACTS (plus de 37 millions de molécules). La fiche d’identification REGISTRY contient le numéro de registre CAS (RN) et les différents noms de la substance qui serviront ensuite pour interroger les banques de données bibliographiques ou factuelles.

* La commande Expand permet de consulter l’index des noms de substances CN (Chemical Name) et donc de savoir si la substance est répertoriée dans REGISTRY

=> FILE REGISTRY

=> E CHLORPHENAMIDINE/CN 5

E1 1 CHLORPHENACYL/CN

E2 1 CHLORPHENADIONE/CN

E3 1 --> CHLORPHENAMIDINE/CN

E4 1 CHLORPHENAMIDINE MONOHYDROCHLORIDE/CN

E5 1 CHLORPHENAMIDINE-MTMC MIXTURE/CN

=> S E3

L1 1 CHLORPHENAMIDINE/CN

* Visualisation de la fiche d’identification

=> D

L1 ANSWER 1 OF 1 REGISTRY COPYRIGHT 2008 ACS on STN

RN 6164-98-3 REGISTRY

ED Entered STN: 16 Nov 1984

CN Methanimidamide, N'-(4-chloro-2-methylphenyl)-N,N-dimethyl- (CA INDEX NAME)

OTHER CA INDEX NAMES:

CN Formamidine, N'-(4-chloro-o-tolyl)-N,N-dimethyl- (7CI, 8CI)

OTHER NAMES:

CN 1-(2-Methyl-4-chlorophenyl)-3,3-dimethylformamidine

CN Acaron

CN C 8514

CN CDM

CN CDM (acaricide)

CN Chlordimeform

CN Chlorophenamidin

CN Chlorophenamidine

CN Chlorphenamidine

CN CIBA 8514

CN Formamidine, N,N-dimethyl-N'-(2-methyl-4-chlorophenyl)-

CN Fundal

CN Fundal 500

CN Galecron

CN N'-(2-Methyl-4-chlorophenyl)-N,N-dimethylformamidine

CN N'-(4-Chloro-2-methylphenyl)-N,N-dimethylmethanimidamide

CN N'-(4-Chloro-o-tolyl)-N,N-dimethylformamidine

CN N'-(p-Chloro-o-tolyl)-N,N-dimethylformamidine

CN N,N-Dimethyl-N'-(2-methyl-4-chlorophenyl)formamidine

CN RS 141

CN Schering 36,268

MF C10 H13 Cl N2

CI COM

LC STN Files: ADISNEWS, AGRICOLA, ANABSTR, AQUIRE, BEILSTEIN*, BIOSIS,

BIOTECHNO, CA, CABA, CAOLD, CAPLUS, CASREACT, CBNB, CHEMCATS, CHEMLIST,

CHEMSAFE, CIN, CSCHEM, CSNB, DDFU, DETHERM*, DRUGU, EMBASE, HSDB*,

IFICDB, IFIPAT, IFIUDB, MEDLINE, MRCK*, MSDS-OHS, PIRA, PROMT, RTECS*,

SPECINFO, TOXCENTER, ULIDAT, USPATFULL, USPATOLD

(*File contains numerically searchable property data)

Other Sources: EINECS**

(**Enter CHEMLIST File for up-to-date regulatory information)

1030 REFERENCES IN FILE CA (1907 TO DATE)

27 REFERENCES TO NON-SPECIFIC DERIVATIVES IN FILE CA

1030 REFERENCES IN FILE CAPLUS (1907 TO DATE)

4 REFERENCES IN FILE CAOLD (PRIOR TO 1967)

* La commande SELECT CHEM va permettre d’extraire de la fiche les multiples noms de la substance (noms commerciaux, triviaux, chimiques) ainsi que le numéro de registre.

=> SELECT CHEM L1 1

E6 THROUGH E27 ASSIGNED

=> D SEL E6-E27

E6 1 ACARON/BI

E7 1 C 8514/BI

E8 1 CDM (ACARICIDE)/BI

E9 1 CDM/BI

E10 1 CHLORDIMEFORM/BI

E11 1 CHLOROPHENAMIDIN/BI

E12 1 CHLOROPHENAMIDINE/BI

E13 1 CHLORPHENAMIDINE/BI

E14 1 CIBA 8514/BI

E15 1 FORMAMIDINE, N,N-DIMETHYL-N'-(2-METHYL-4-CHLOROPHENYL)-/BI

E16 1 FUNDAL 500/BI

E17 1 FUNDAL/BI

E18 1 GALECRON/BI

E19 1 N,N-DIMETHYL-N'-(2-METHYL-4-CHLOROPHENYL)FORMAMIDINE/BI

E20 1 N'-(P-CHLORO-O-TOLYL)-N,N-DIMETHYLFORMAMIDINE/BI

E21 1 N'-(2-METHYL-4-CHLOROPHENYL)-N,N-DIMETHYLFORMAMIDINE/BI

E22 1 N'-(4-CHLORO-O-TOLYL)-N,N-DIMETHYLFORMAMIDINE/BI

E23 1 N'-(4-CHLORO-2-METHYLPHENYL)-N,N-DIMETHYLMETHANIMIDAMIDE/BI

E24 1 RS 141/BI

E25 1 SCHERING 36,268/BI

E26 1 1-(2-METHYL-4-CHLOROPHENYL)-3,3-DIMETHYLFORMAMIDINE/BI

E27 1 6164-98-3/BI

2° Interrogation des banques de données bibliographiques 

* Création d’un cluster (SET CLUSTER) c'est-à-dire d’un ensemble de banques de données bibliographiques, celles qui contiennent le plus d’informations dans le domaine de l’écotoxicologie (cette procédure s’effectue une fois pour toutes)

=> SET CLUSTER

ENTER CLUSTER NAME OR (?):.ECOTOX

ENTER LIST OF FILE NAMES OR (?):ESBIOBASE TOXCENTER PASCAL MEDLINE EMBASE BIOSIS HCAPLUS SCISEARCH AQUASCI WATER AQUALINE

MORE FILES, (NONE) OR ?:.

CLUSTER '.ECOTOX' DEFINED AS 'ESBIOBASE, TOXCENTER, PASCAL, MEDLINE, EMBASE,

BIOSIS, HCAPLUS, SCISEARCH, AQUASCI, WATER, AQUALINE'

SET COMMAND COMPLETED

* Recherche exploratoire (INDEX) menée dans le cluster .ECOTOX sur les noms ou le RN ; cette première étape permet d’identifier les banques de données qui contiennent des réponses

=> INDEX .ECOTOX

INDEX 'ESBIOBASE, TOXCENTER, PASCAL, MEDLINE, EMBASE, BIOSIS, HCAPLUS,

SCISEARCH, AQUASCI, WATER, AQUALINE' ENTERED AT 14:12:20 ON 20 AUG 2008

11 FILES IN THE FILE LIST IN STNINDEX

=> S E6-E27 AND ECOTOX?

7 FILE ESBIOBASE

3 FILE TOXCENTER

1 FILE PASCAL

2 FILE EMBASE

4 FILE HCAPLUS

1 FILE SCISEARCH

6 FILES HAVE ONE OR MORE ANSWERS, 11 FILES SEARCHED IN STNINDEX

L2 QUE (ACARON/BI OR "C 8514"/BI OR "CDM (ACARICIDE)"/BI OR CDM/BI OR CHLORDI

MEFORM/BI OR CHLOROPHENAMIDIN/BI OR CHLOROPHENAMIDINE/BI OR CHLORPHENA

MIDINE/BI OR "CIBA 8514"/BI OR "FORMAMIDINE, N,N-DIMETHYL-N'-(2-METHYL

-4-CHLOROPHENYL)-"/BI OR "FUNDAL 500"/BI OR FUNDAL/BI OR GALECRON/BI O

R "N,N-DIMETHYL-N'-(2-METHYL-4-CHLOROPHENYL)FORMAMIDINE"/BI OR "N'-(P-

CHLORO-O-TOLYL)-N,N-DIMETHYLFORMAMIDINE"/BI OR "N'-(2-METHYL-4-CHLOROP

HENYL)-N,N-DIMETHYLFORMAMIDINE"/BI OR "N'-(4-CHLORO-O-TOLYL)-N,N-DIMET

HYLFORMAMIDINE"/BI OR "N'-(4-CHLORO-2-METHYLPHENYL)-N,N-DIMETHYLMETHAN

IMIDAMIDE"/BI OR "RS 141"/BI OR "SCHERING 36,268"/BI OR "1-(2-METHYL-4

-CHLOROPHENYL)-3,3-DIMETHYLFORMAMIDINE"/BI OR 6164-98-3/BI) AND ECOTOX?

* Classement des banques de données en fonction du nombre de réponses obtenues

=> D RANK

F1 7 ESBIOBASE

F2 4 HCAPLUS

F3 3 TOXCENTER

F4 2 EMBASE

F5 1 PASCAL

F6 1 SCISEARCH

* Entrée et recherche dans ces banques de données, puis élimination des doublons (DUPlicate REMove)

=> FILE HITS

=> S L2

L3 7 FILE ESBIOBASE

L4 4 FILE HCAPLUS

L5 3 FILE TOXCENTER

L6 2 FILE EMBASE

L7 1 FILE PASCAL

L8 1 FILE SCISEARCH

TOTAL FOR ALL FILES

L9 18 L2

=> DUP REM L9

L10 15 DUP REM L9 (3 DUPLICATES REMOVED)

ANSWERS '1-7' FROM FILE ESBIOBASE

ANSWERS '8-11' FROM FILE HCAPLUS

ANSWERS '12-13' FROM FILE EMBASE

ANSWER '14' FROM FILE PASCAL

ANSWER '15' FROM FILE SCISEARCH

* Visualisation de la première référence de chaque banque de données (BIBliographie +

mots interrogés Keyword In Context). Pour visualiser la totalité des références avec résumé,

utiliser la commande D BIB ABS TOT

=> D BIB KWIC FROM EACH

L10 ANSWER 1 OF 15 Elsevier BIOBASE COPYRIGHT 2008 Elsevier Science B.V. on STN

AN 2004273389 ESBIOBASE Full-text <<LOGINID::20080820>>

TI Cultured neuronal networks as environmental biosensors

AU O'Shaughnessy T.J.; Gray S.A.; Pancrazio J.J.

CS T.J. O'Shaughnessy, Ctr. for Bio/Molec. Sci./Engineering, Naval Research

Laboratory, Washington, DC 20375, United States.

E-mail: tjo@cbmse.nrl.navy.mil

SO Journal of Applied Toxicology, (2004), 24/5 (379-385), 16 reference(s)

CODEN: JJATDK ISSN: 0260-437X

DT Journal; Article

CY United Kingdom

LA English

AB . . . detected for four of the compounds at concentrations below a lethal

level for humans: mercuric chloride, sodium arsenite, phosdrin and

chlordimeform. These compounds - two heavy metals, an organophosphate

and an insecticide - demonstrate the breadth of detection possible with

neuronal. . .

CC 90.12.8.2 TOXICOLOGY: TOXICITY STUDIES IN OTHER ORGANISMS AND

ECOTOXICOLOGY: Methods: Toxicity tests

L10 ANSWER 8 OF 15 HCAPLUS COPYRIGHT 2008 ACS on STN DUPLICATE 1

AN 1999:487805 HCAPLUS Full-text <<LOGINID::20080820>>

DN 131:238992

TI Subclinical Health Effects of Environmental Pesticide Contamination in a

Developing Country: Cholinesterase Depression in Children

AU McConnell, Rob; Pacheco, Feliciano; Wahlberg, Kare; Klein, Willy;

Malespin, Omar; Magnotti, Ralph; Aakerblom, Malin; Murray, Douglas

CS Department of Preventive Medicine, University of Southern California

School of Medicine, Los Angeles, CA, 90033, USA

SO Environmental Research (1999), 81(2), 87-91

CODEN: ENVRAL; ISSN: 0013-9351

PB Academic Press

DT Journal

LA English

RE.CNT 21 THERE ARE 21 CITED REFERENCES AVAILABLE FOR THIS RECORD

ALL CITATIONS AVAILABLE IN THE RE FORMAT

IT Air pollution

Ecotoxicity

Environmental pollution

Health hazard

Pesticides

Water pollution

(pesticide ecotoxicity in relation to subclin. health effects

of environmental pesticide contamination in a developing country and

cholinesterase depression in children)

IT 50-29-3, DDT, biological studies 55-38-9, Fenthion 58-89-9, Lindane

72-54-8, DDD 72-55-9, DDE, biological studies 298-00-0,

Methylparathion 319-85-7, b-HCH 333-41-5, Diazinon 950-10-7,

Mephosfolan 2921-88-2, Chlorpyrifos 3761-41-9, Fenthion sulfoxide

6164-98-3 8001-35-2, Toxaphene

RL: ADV (Adverse effect, including toxicity); POL (Pollutant); BIOL

(Biological study); OCCU (Occurrence)

(pesticide ecotoxicity in relation to subclin. health effects

of environmental pesticide contamination in a developing country and

cholinesterase depression in children)

L10 ANSWER 12 OF 15 EMBASE COPYRIGHT (c) 2008 Elsevier B.V. All rights

reserved on STN

AN 2008368904 EMBASE Full-text <<LOGINID::20080820>>

TI Density, distribution and control of flies in the camps of

earthquake-rescue troops in Yingxiu Town of Wenchuan County.

AU Cheng, Wen-Jun; Zhang, Qian; Zhu, Shi-Ying; Ruan, Fang-Ming; Cao,

Guang-Wen (correspondence)

CS Number 2 Epidemic Prevention Team for Earthquake Rescue, Second Military

Medical University, Shanghai 400433, China. zhqiank@hotmail.com;

gcao@smmu.edu.cn; cwjcwj1976@yahoo.com.cn

SO Academic Journal of Second Military Medical University, (Jul 2008) Volume

29, Number 7, pp. 734-736.

Refs: 3

ISSN: 0258-879X CODEN: DJXUE5

CY China

DT Journal; Article

FS 017 Public Health, Social Medicine and Epidemiology

004 Microbiology: Bacteriology, Mycology, Parasitology and Virology

046 Environmental Health and Pollution Control

LA Chinese

SL Chinese; English

ED Entered STN: 8 Aug 2008

Last Updated on STN: 8 Aug 2008

AB . . . and garbage dumping grounds. More flies were found in the hot, sunshine weather than in the cool, cloudy weather. Insecticide chlordimeform was very effective in controlling the flies. Insecticide-resistance was not observed. Conclusion: The deteriorating environment around the camps is the. . .

CT Medical Descriptors:

army

article

China

*disaster

disinfection

earthquake

ecotoxicology

environmental management

environmental sanitation

incidence

*infection control

insecticide resistance

military service

mosquito

nonparametric test

police

rescue personnel

risk reduction

sanitation

Student t test

*vector control

chlorphenamidine

glue

insecticide

RN (chlorphenamidine) 6164-98-3

L10 ANSWER 14 OF 15 PASCAL COPYRIGHT 2008 INIST-CNRS. ALL RIGHTS RESERVED.

on STN

AN 1997-0285016 PASCAL Full-text <<LOGINID::20080820>>

TIEN Agrochemicals as probes in the life sciences

AU VOSS G.

SO Chemtech, (1997), 27(4), 17-24, 27 refs.

ISSN: 0009-2703 CODEN: CHTEDD

DT Journal